Esophageal cancer forms in tissues lining the esophagus (the muscular tube through which food passes from the throat to the stomach). The two main types are squamous cell carcinoma (cancer that begins in flat cells lining the esophagus) and adenocarcinoma (cancer that begins in cells that make and release mucus and other fluids). The disease is much more common in men than women, but is relatively rare compared to the more common cancers like breast, colon and prostate.

Our Esophageal Cancer Treatment combination outperformed all others.

In a recently completed clinical trial, Marin General Hospital delivered a combination of treatment that performed better than all other methods at all other sites in similar national studies. Esophageal cancer is relatively rare, so patient outcomes in all stages of the disease were combined. Typical treatment methods include: chemotherapy, radiation therapy and surgery, either alone or in some combination.

We compared our results to 5 other nationally known studies.

  • 2 studies used chemotherapy and radiation therapy without surgery
  • 2 studies compared chemotherapy and surgery versus surgery alone
  • 1 study compared chemotherapy, radiation therapy and surgery vs. surgery alone
  • Our study delivered patients an individualized combination of chemotherapy, followed by chemotherapy with radiation therapy, plus surgery for a carefully selected group we felt would benefit from this regimen. Of all participants (41 patients), only about 25% had surgery. This combination provided the best outcomes over the 10 year period.